林原，博士，教授。林原于1982年7月于上海醫科大學（現復旦大學上海醫學院）獲學士學位；1985年7月于上海第二醫科大學（現上海交通大學醫學院）獲碩士學位；1992年6月于日本群馬大學醫學部獲博士學位；1996年4月至1998年4月應日本學術振興會的邀請赴日進行博士后研究。1998年起至今為大連醫科大學教授，2000年起至今為博士生導師。
科研情況
（1）主持完成國家自然科學基金項目：（a）“平滑肌肌球蛋白活性的雙向調節研究”,項目編號：No:30772601；（b）“肌球蛋白輕鏈激酶對肌球蛋白的非鈣依賴性磷酸化研究”項目編號：30070203; （c）“肌球蛋白與肌動蛋白相互作用調節中的“雙向調節”機制”, 項目編號：39670166。
研究方向
胃腸道藥理學。胃腸道等重要器官的疾病與平滑肌功能變化密切相關。多種原因可造成平滑肌收縮舒張的失調。炎癥、便秘、腹瀉、收縮性的亢進與不足等癥狀皆可能交替存在互相影響。（1）不同于藥物結構-效應之間的關系，也不同于由于存在作用相反化學成分或使用劑量不同所造成的雙向調節，本研究室探討腸平滑肌收縮狀態決定藥物的效應是興奮性的或抑制性的規律性，為開發對于腸平滑肌收縮舒張具有雙向調節的藥物打下基礎。（2）探討藥物對腸道炎癥的緩解作用。
培養研究生情況
本研究已培養畢業博士生7名。研究組近5年來，研究生共發表SCI引用雜志發表文章19篇。其中，2013及2014畢業的兩位博士研究生個人發表SCI累計影響因子皆在10分以上。本研究室畢業的研究生相當一部分目前任職在高校教學與科研崗位或成為知名公司的骨干，活躍于國際與國內科研教學崗位上。
代表性文章（* 通訊作者）
1. Xiong YJ, Chen DP, Yu CC, Lv BC, Peng JY, Wang JY, and Lin Y(林原，通訊)*. Citrus nobiletin ameliorates experimental colitis by reducing inflammation and restoring impaired intestinal barrier function. Mol Nutr Food Res. 2015, Feb 6 (已接受并已在PubMed 上發表). doi: 10.1002/mnfr.201400614.
2. Xiong YJ， Chen, D Peng JY, Wang, JY, Lv, BC, Liu FF, Lin, Y(林原，通訊)* Characteristics of evodiamine-exerted stimulatory effects on rat jejunal contractility. Nat Prod Res, 2015, 29: 388 - 391.
3. Yao, QY, Chen, DP, Ye, DM, Diao, YP, Lin, Y(林原，通訊)*. Modulatory effects of taurine on jejunal contractility. Braz J Med Biol Res, 2014, 47: 1068 -1074.
4. Chen DP, Xiong, YJ, and Lin Y(林原，通訊)*. Dual Role of MAPK Pathway in the Regulation of Intestinal Barrier Function. Inflamm Bowel Dis, 2014, 20: E16 - E16.
5. Xiong YJ, Chen, DP, Lv, BC; Liu, FF Yao, QY, Tang, ZY, Lin, Y(林原，通訊)*.Effects of ginsenoside Re on rat jejunal contractility. J Nat Med, 2014, 68: 530 - 538.
6. Xiong YJ, Chen DP, Lv BC, Liu FF, Wang Li, and Lin Y(林原，通訊)*. Characteristics of nobiletin-induced effects on jejunal contractility. Fitoterapia, 2014, 94: 1 - 9.
7. Liu FF, Chen, DP, Xiong, YJ Lv, BC, Lin, Y(林原，通訊)*. Characteristics of Diprophylline-Induced Bidirectional Modulation on Rat Jejunal Contractility. Korean J Physiol & Pha, 2014, 18: 47 - 53.
8. Chen DP, Xiong, YJ, Jiang CL, Lv BC, Liu FF, Wang L, Lin Y(林原，通訊)*. Effects of ginsenosides on rat jejunal contractility. Pharm Biol, 2014, 52: 162 - 168.
9. Chen, DP, Lin, Y (林原，通訊)*, X YJ. Epithelial MLCK and Smooth Muscle MLCK May Play Different Roles in the Development of Inflammatory Bowel Disease. Digest Dis Sci, 2014, 59: 1068 - 1069.
10. Zhang Y, Zhang, HL, Tang, ZY, Kohama, K, Lin, Y (林原，通訊)*. Inverse interaction between tropomyosin and phosphorylated myosin in the presence or absence of caldesmon. Acta Bioch Bioph Sin, 2013, 45 : 601 - 606.
11. Chen DP, Xiong YJ, Lv BC, Liu FF, Wang L, Tang ZY, Lin Y(林原，通訊)*. Effects of berberine on rat jejunal motility. J Pharm Pharmacol, 2013, 65:734-744.
12. Yao QY, Wang L, Du Z, Li K, Lin Y(林原，通訊)*. Characterization and biological evaluation of structurally modified taurine using benzaldehydes. Asian J Chem, 2013, 25: 7843 - 7846.
13. Ye DM, Zhang, HL, Wang L, Yao QY, Lin Y(林原，通訊)*., Li K. Synthesis, Crystal Structural and Activities of a New Schiff Base Derived from 2,4,5-Trimethoxybenzaldehyde. Asian J Chem, 2013, 25: 4629 - 4631.
14. Xiong YJ, Chen DP, Lv, BC, Liu, FF, Wang, L, Lin, Y. The characteristics of genistin-induced inhibitory effects on intestinal motility. Arch Phar Res, 2013, 36 : 345 - 352.
15. Chen DP, Xiong YJ, Tang ZY, Yao QY, Ye DM, Liu SS, Lin Y(林原，通訊)*. Characteristics of deslanoside-induced modulation on jejunal contractility. World J. Gastroentero, 2012, 18: 5889-5896. 10.3748/wjg.v18.i41.5889.
16. Chen DP, Xiong YJ, Wang L, Lv BC, Lin Y(林原，通訊)*.. Characteristics of emodin on modulating the contractility of jejunal smooth muscle. Can J Physiol Pharm, 2012, 90 : 455 - 462.
17. Chen DP, Xiong YJ, Tang ZY, Lv, BC, Lin Y(林原，通訊)*. Inhibitory effects of daidzein on intestinal motility in normal and high contractile states. Phar Biol, 2012, 50: 1561 - 1566.
18. Zhang Y, Tang, ZY, Kohama K, and Lin Y(林原，通訊)*. Interaction between myosin and a trace amount of caldesmon. J Biochem, 2011, 150: 267 - 270.
19. Tang ZY, Liu ZN, Fu L, Chen, DP, Ai QD, Lin Y. Effect of lithium on smooth muscle contraction and phosphorylation of myosin Light chain by MLCK. Physiol Res, 2010, 59: 919 - 926.
